relief of osteoarthritis with Tylenol (acetaminophen) is not effective: Study ; Home “ bone health “
Tylenol (acetaminophen) is not effective Osteoarthritis relief. A study showed that Tylenol is performed slightly better than placebo, but the researchers suggest that non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) or diclofenac are better treatment options for osteoarthritis pain and the role of Tylenol.
The principal investigator Dr. Sven Trelle said, “regardless of dose, diclofenac prescription drug is the most effective drug among analgesics in terms of improving pain and function osteoarthritis. If you are thinking of using a pain reliever for osteoarthritis, you should consider diclofenac. “the long-term use of NSAIDs has been shown to increase the risk of heart disease and even death.
maker of Tylenol had some problems with the findings and issued a statement saying: “We do not agree with the interpretation of the authors of this meta-analysis and we paracetamol remains an option of relieving severe pain for million consumers, particularly those with certain conditions that NSAIDs may not be appropriate -. including cardiovascular disease, gastrointestinal bleeding, and kidney disease [kidney] the safety profile and effectiveness of paracetamol is supported by more than 150 studies in the last 50 years. ”
While arthritis is an inflammatory disease, such as Tylenol acetaminophen products do not address inflammation . This explains why these drugs are not effective for osteoarthritis.
The study analyzed 74 previously published trials, including more than 58,000 patients. The study compared the effectiveness of different doses of acetaminophen along with seven different NSAIDs to treat arthritis pain.
Acetaminophen performed slightly better than placebo, but when taken alone, has not been found to be effective in relieving symptoms associated with osteoarthritis regardless of dose.
Maximum daily dose of diclofenac was found
to be the most successful in the treatment of osteoarthritis. Dr. Nicholas Moore, the department of pharmacology at the University of Bordeaux in France said: “Acetaminophen may not be as safe as most people believe: is known to be toxic to the liver, and .. acetaminophen overdose is the leading cause of transplant liver NSAIDs are the most effective analgesics, and avoid putting patients at risk for acetaminophen overdose “
Moore suggested:” We must look also to the older drugs that may have been discarded, and perhaps work harder to understand the mechanism of action of paracetamol to develop a new, more effective and less toxic than the same class, or develop new classes of analgesics “drug.
medication options osteoarthritis pain
There are a variety of different pain medications available to relieve symptoms associated with osteoarthritis based on their gravity. For less severe pain, NSAIDs have proven effective, with the cyclooxygenase-2 (COX-2), prescription NSAIDs cause less stomach irritation, compared to over-the-counter NSAIDs.
For severe osteoarthritis pain , the doctor would be more inclined towards a prescription, including opioid analgesics, corticosteroid injections, and injections hyaluronic acid. It is important to note that long-term use of corticosteroids has been associated with many complications, so the long-term use is not recommended. They are meant to be taken for a short period to provide immediate relief.
Working with your doctor can help you find the best treatment option for the symptoms of osteoarthritis. As a complement to therapies such as rest, ice and physical therapy can help in treatment effectiveness, too.
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