Multiple sclerosis and reducing overactive bladder cause serotonin and cortisol levels of brain: Study

Multiple sclerosis and reducing overactive bladder cause serotonin and cortisol levels of brain: Study ; Home bladder multiple sclerosis and overactive bladder reduction cause General Health serotonin and cortisol levels brain: Study

By: Dr. Victor Marchione | bladder | Tuesday, June 28, 2016 – 12:00 pm

Multiple sclerosis and overactive bladder cause reduction in brain serotonin and cortisol levels: Study Multiple sclerosis (MS) and overactive bladder (OAB) reducing the cause of cerebral serotonin and cortisol levels. Serotonin is a chemical messenger that facilitates communication of nerve cells, while cortisol is a hormone associated mainly with a stress response. quite common in multiple sclerosis, bladder problems may also be one of the first symptoms of multiple sclerosis.

The nervous system is very involved in the process of urination and, as we know, multiple sclerosis primarily affects the nervous through the destruction of myelin system, the protective layer around nerves and spinal cord.

The researchers studied 101 patients with multiple sclerosis, assessing symptoms of an overactive bladder and measurement of several biomarkers in the cerebrospinal fluid of the study subjects. Biomarkers including neurotransmitters and stress hormones.

Among participants who had fifteen overactive bladder, researchers found a reduction of a degradation product of the neurotransmitter serotonin (5-HIAA) -. Compared with participants who have overactive


The researchers said that “patients with multiple sclerosis and overactive bladder syndrome in the first show a decrease of demyelinating episode of serotonergic activity and hormones of central stress. If these changes persist in the later stages of the disease it has not yet been investigated. ”

Further research will explore whether this pattern continues in the later stages of multiple sclerosis in patients with overactive bladder. Identified biomarkers can be potentially used to detect multiple sclerosis.

Overactive bladder in patients with multiple sclerosis

MS patients can experience variety of bladder problems , including nocturia, urinary urgency, incontinence , and difficulty urinating. Nocturia is a condition in which a person wakes up several times during the night to urinate. urinary urgency is when a person feels a strong need to urinate and yet only a small amount leaving. Incontinence is loss of bladder control causing leakage, while urinary hesitation is when it is difficult to start urinating.

Intestinal problems, too, can be a problem for patients with multiple sclerosis may experience constipation and fecal incontinence. Fecal incontinence is the loss of control over bowel movements one.

Get control of your bladder is important, especially if you have multiple sclerosis. Here are some tips that you can try in order to improve the management and treatment of bladder symptoms related to multiple sclerosis

  • Change your diet and consume less fluids before bedtime, but make sure you are not dehydrated.
  • talk to your doctor about specific medications that can help control bladder symptoms.
  • try physical therapy pelvic floor, using the pelvic floor training, biofeedback, neuromuscular stimulation and daily exercises at home to reduce urinary frequency and urgency and the treatment of loss of bladder control .
  • Consider percutaneous tibial nerve stimulation (PTNS), where a needle is inserted into the ankle to stimulate the tibial nerve. It is believed that PTNS weekly treatments to inhibit overactive bladder.
  • Consult your doctor about intermittent catheterization (ISC), in which a catheter for those who have difficulty emptying the bladder is inserted.

In order to choose the right treatment for optimal relief, it is important to talk to your doctor and discuss your symptoms.
Even if you have multiple sclerosis, you need not be a victim of the bladder. The first step is to open the conversation to address your specific needs.


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